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David Axelbank

David Axelbank was born in Shrewsbury, UK in 1972. He was raised in the Soviet Union, Israel, England and America. He attended the State University of New York (SUNY) at Purchase earning a Bachelor of Fine Art with a concentration in Photography and Printmaking, in 1994.

From 1993, Axelbank worked at Magnum Photos New York, as assistant to the Bureau Chief; historical researcher for Susan Meiselas’s Kurdistan book; and then full-time in the Editorial Department. He moved to San Francisco in 1996 to pursue freelance photographic assignments. After relocating to London in 2000 he began working for Magnum Photos as the Production Manager. During this time he was involved in the setting up of Magnum and HP’s creative partnership, printed numerous international exhibitions, and worked closely with Magnum photographers on the production of their projects.

Leaving Magnum in 2006 to pursue photography full-time, he has since worked for clients such as The Gap, Grazia, TimeOut, Tank and The Drawbridge. In 2005 Axelbank’s work was selected for the Schweppes Photographic Portrait Award exhibited at National Gallery, London. In 2009, his Flora series was shortlisted for the Descubrimientos PHE Madrid (Discovery Award) at PhotoEspaña and included in the Creative Review Photography Annual 2009. He teaches photography at Photofusion in Brixton, is a Lecturer in Photography at the University of Hertfordshire, and a visiting lecturer at Anglia Ruskin.

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    • ‘Artichoke Flower’
      David Axelbank

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WebMD Feature Recommendation 2: The American College of Physicians recommends that clinicians base the choice of a specific PDE-5 inhibitor on the individual preferences of men with erectile dysfunction, including ease of use, cost of medication, and adverse effects profile (Grade: weak recommendation; low-quality evidence). Decreased free T4 Hyperthyroidism Heat intolerance; weight loss; diaphoresis; palpitations Lid lag; exophthalmos; hyperreflexia; tremor; tachycardia Decreased TSH "Women internalize things -- they tend to blame themselves first, thinking it's because they have done something wrong, or that they are no longer attractive to their partner. In fact, the first thing a woman thinks when a man can't get an erection is that it's her fault, and nothing could be further from the truth," says Andrew McCullough, MD, director of sexual health and male infertility at NYU Medical Center in New York City. real viagra Despite traditional views about the effects of booze on male performance, new research suggests that moderate drinking actually protects against impotence in the long term – perhaps for the same reason a glass or two of wine a day cuts the odds of suffering from heart disease. "Most women usually start with a line of questioning that often has some anxiety or hurt to it. She may suspect her partner is having an affair, or that he just doesn't find her desirable anymore, so she begins to hint around at these possibilities," says Sallie Foley, MSW, a professor at the graduate school of social work at the University of Michigan and co-author of Sex Matters For Women. The TV commercials make it all seem so simple: He can't get an erection so he pops a pill. The next thing you know, his partner is cooing about how her guy is back to his old wild and romantic self. Injection therapy Therefore, men who produce too little cyclic GMP and men who produce too much PDE5 have problems obtaining and maintaining an erection. "No in-vivo studies in an animal model have been performed at this regard, so a lot of work must be done. We would like to test in vivo [with animals] the molecule to understand if it really works in humans," said study lead author Mario Dell'Agli, of the University of Milan's laboratory of pharmacognosy. "At this stage of the research, we cannot say if the molecule we have synthesized possesses less side effects with respect to Viagra. However, this derivative seems to be in vitro [in lab tests] more selective than Viagra, because it targets [an enzyme involved in blood flow to the penis] more precisely." Tests that may be done include: Missed Signals "For men getting a high dose of radiation in a shorter amount of time than is typical -- meaning getting higher doses per day for fewer days -- a loss of sexual function is the chronic side effect that concerns most," noted study co-author Dr. Eric Horwitz, a clinical director in the department of radiation oncology at Fox Chase Medical Center in Philadelphia. Erectile dysfunction (ED), also called impotence, affects most men at some point during their lifetime. However, chronic impotence may indicate a medical condition, such as heart disease, high blood pressure, high cholesterol, kidney disease, or diabetes. The causes may be physiological or psychological. Psychological impotence can often be helped by almost anything that the patient believes in; there is a very strong placebo effect. viagra online sale Abstract DRAMATIC ADVANCES IN THE MANAGEMENT of erectile dysfunction have occurred over the past decade. Oral therapy with vasoactive agents has emerged as first-line treatment and has transformed both the manner in which the public views erectile dysfunction and the way health care providers deliver care. Whereas an extensive investigation was previously common in the management of erectile dysfunction, recent treatment guidelines promote a more minimalist, goal-oriented approach. In this article, we review the physiology of erection, and the pathophysiology, diagnosis and clinical management of erectile dysfunction. We also present the existing evidence for the efficacy of 3 phosphodiesterase inhibitors, the most widely used class of agents for erectile dysfunction. Treating heart disease risk factors Phosphodiesterase-5 (PDE5) inhibitors (sildenafil, tadalafil, and vardenafil) are agents currently in clinical use for nonmalignant conditions. We report the use of PDE5 inhibitors as modulators of the antitumor immune response. In several mouse tumor models, PDE5 inhibition reverses tumor-induced immunosuppressive mechanisms and enables a measurable antitumor immune response to be generated that substantially delays tumor progression. In particular, sildenafil, down-regulates arginase 1 and nitric oxide synthase–2 expression, thereby reducing the suppressive machinery of CD11b+/Gr-1+ myeloid-derived suppressor cells (MDSCs) recruited by growing tumors. By removing these tumor escape mechanisms, sildenafil enhances intratumoral T cell infiltration and activation, reduces tumor outgrowth, and improves the antitumor efficacy of adoptive T cell therapy. Sildenafil also restores in vitro T cell proliferation of peripheral blood mononuclear cells from multiple myeloma and head and neck cancer patients. In light of the recent data that enzymes mediating MDSC-dependent immunosuppression in mice are active also in humans, these findings demonstrate a potentially novel use of PDE5 inhibitors as adjuncts to tumor-specific immune therapy.

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